1 in 5 people may carry this hidden genetic heart risk

New research presented at the SCAI 2026 sessions indicates that one in five people may have elevated levels of Lipoprotein(a), a genetic factor that increases cardiovascular risk. The study suggests that standard cholesterol treatments may not be sufficient for these individuals, necessitating more aggressive risk management.
New findings from more than 20,000 patients across three major NIH studies suggest that elevated Lipoprotein(a) [Lp(a)] may contribute to cardiovascular risk that remains even after standard treatment. The results indicate that people with high Lp(a) may benefit from more aggressive efforts to reduce other heart disease risk factors.
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