Science Daily·4 min read·medium
A hidden weakness in deadly cancers could lead to powerful new treatments

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UCLA researchers have discovered that certain aggressive cancers lacking the RB gene are highly dependent on the E2F3 protein for survival. This 'synthetic lethality' provides a potential new target for developing therapies for previously untreatable tumors.
Researchers at UCLA have identified a hidden weakness in some of the most aggressive and difficult-to-treat cancers, raising hopes for a new way to attack tumors that have resisted treatment for decades.
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