European AIDS Treatment Group·3 min read·hard

[AIDS 2026] MedPage Today: Long-acting lenacapavir still delivered effective HIV PrEP after a year

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[AIDS 2026] MedPage Today: Long-acting lenacapavir still delivered effective HIV PrEP after a year
AI Summary

Clinical trial extensions for the injectable HIV prevention drug lenacapavir have shown high efficacy with almost no new infections reported over a year. The study included diverse populations across South Africa, Uganda, and other regions.

Only one person has developed a new HIV infection during a year-long extension of the landmark PURPOSE 1 and PURPOSE 2 trials testing twice-yearly injectable lenacapavir (Yeztugo) for PrEP, according to twin open-label extensions.

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