Chemotherapy's Genomic Traces in Childhood Cancer Unveiled
A study led by The Hospital for Sick Children has discovered that chemotherapy leaves distinct genomic signatures in childhood cancer cells within 18 months of treatment. These findings could help clinicians identify treatment resistance earlier and improve long-term patient outcomes.
Nearly half of childhood tumours treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). Researchers say these changes could eventually help clinicians spot treatment resistance earlier, before cancer returns or spreads, opening the door to a more precise use of chemotherapy.
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