Editor's Pick: Retrospective Cohort Study of Long-Term Outcomes Associated with Severe Hyponatraemia

A retrospective cohort study of 202 patients reveals that severe hyponatraemia is associated with high 18-month mortality rates. The study suggests that while hypertonic saline treatment can reduce mortality, rapid correction carries risks of neurological complications.
Hyponatraemia is the most common electrolyte abnormality among hospital inpatients. This retrospective cohort study examined demographic characteristics, diagnostic investigations, clinical management, and outcomes of patients admitted with severe hyponatraemia (serum sodium ≤120 mmol/L) over an 18-month period.
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