Experimental drug reverses severe fatty liver disease by repairing the gut

Researchers at the University of Michigan have developed an experimental drug called DT-109 that reverses severe fatty liver disease in animal models. The drug works by repairing the gut barrier and preventing harmful bacterial products from triggering liver inflammation.
An experimental drug developed at Michigan Medicine has shown the ability to reverse severe fatty liver disease in animal studies by restoring gut health. The findings, published in The Journal of Clinical Investigation , suggest that targeting the connection between the gut and liver could offer a promising new approach for treating metabolic dysfunction-associated steatohepatitis (MASH).
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