Science Daily·3 min read·medium

Oral GLP-1 drugs may quiet the brain’s food craving circuit

Oral GLP-1 drugs may quiet the brain’s food craving circuit
AI Summary

Researchers have identified a new neural pathway in the brain that oral GLP-1 medications target to reduce hedonic eating. This discovery suggests these drugs could potentially treat reward-based conditions like substance use disorder in addition to obesity.

Popular weight-loss and diabetes medications such as semaglutide and Ozempic belong to a broader group known as GLP-1 drugs. A study funded by the National Institutes of Health (NIH) has now identified a previously unrecognized way that some newer oral drugs in this class may affect the brain.

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