Science Daily·3 min read·medium

Without this protein, damaged muscle turns to fat and scar tissue

Without this protein, damaged muscle turns to fat and scar tissue
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Researchers have discovered that the protein TRF2, typically known for protecting chromosome ends, is vital for muscle stem cell regeneration. Without this protein, damaged muscle tissue fails to repair properly and instead turns into fat and scar tissue.

A protein traditionally associated with protecting chromosome ends also plays an unexpected role in helping muscle stem cells remain functional and rebuild injured tissue, according to researchers at the Perelman School of Medicine at the University of Pennsylvania. The discovery could guide future research into muscular dystrophy treatments while also offering broader clues about cancer biology.

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